Dr. Jinae Roa is a native of southern California. She received a BS in Biology from UC Santa Barbara and an MS in Biology from CSU Long Beach, where she specialized in muscle physiology of marine fish. Dr. Roa completed her doctoral research as a member of the Tresguerres Laboratory and received a PhD in Marine Biology from Scripps Institution of Oceanography at UC San Diego, where she specialized in acid-base physiology of marine elasmobranchs. She continued her training as an NSF Postdoctoral Research Fellow in the laboratories of Professors Martin Tresguerres and Colin Bauner at Scripps Institution of Oceanography and the University of British Columbia, then as an NIH IRACDA Postdoctoral Fellow in the laboratories of Professors Susan Taylor and Dorota Skowronska-Krawczykat UC San Diego.
- Acid-base sensing and regulation
- Cell physiology
- Energy metabolism
At SIO, Dr. Roa’s research focuses on mechanisms for acid-base sensing and regulation by the acid-base sensor soluble adenylyl cyclase (sAC) and energy metabolism in marine animals.
Roa JN, Tresguerres M. 2019. Differential glycogen utilization in shark acid- and base-regulatory cells. Journal of Experimental Biology 222.
Roa JN, Tresguerres M. 2017. Bicarbonate-sensing soluble adenylyl cyclase is present in the cell cytoplasm and nucleus of multiple shark tissues. Physiological Reports 5: e13090.
Roa JN, Tresguerres M. 2016. Soluble adenylyl cyclase is an acid-base sensor in epithelial base-secreting cells. American Journal of Physiology, Cell Physiology 311: C340–C349.
Wilson CM‡, Roa JN‡, Cox GK, Tresguerres M, Farrell AP. 2016. Introducing a novel mechanism to control heart rate in the ancestral pacific hagfish. Journal of Experimental Biology 219: 3227–3236.
‡Equal author contributions
Tresguerres M, Barott KL, Barron ME, Roa JN. 2014. Established and potential physiological roles of bicarbonate-sensing soluble adenylyl cyclase (sAC) in aquatic animals. Journal of Experimental Biology 217: 663–672.
Roa JN, Munévar CL, Tresguerres M. 2014. Feeding induces translocation of vacuolar proton ATPase and pendrin to the membrane of leopard shark (Triakis semifasciata) mitochondrion-rich gill cells. Comparative Biochemistry and Physiology, Part A: Molecular & Integrative Physiology 174: 29–37.